Synthesis, Characterization and Biological Activity of Two Phenol- Schiff Bases and Formaldehyde Resin Cobalt (Ii) – Complexes.

Abstract

Transition metal, cobalt (II) acetate, complexes of salicylaldehyde derived Schiff bases : 2-{[(2- hydroxophenyl) imino] methyl} phenol (OHMP), 2-{[ (2- carboxy- phenyl) imino] methyl} phenol (COOHMP), and anthranilic acid- formaldehyde resin (R-COOHMP) were synthesized and characterized by various analytical and spectroscopic studies ( FT-IR, UV-Visible and 1H NMR ). The Schiff base ligands,  formaldehyde chelating resin and their Co(II) complexes were also screened for their urease, α – chymotrypsin, acetylcholinesterse and butylrylcholinesterase  inhibition activities. The ligands were found active against two bacterial species: Staphylococcus aureus and Escherichia coli, all theligands and complexes were evaluated for their thermal degradation studies using TG- DTA analytical methods in static air

Keywords: Biological Activity, Cobalt(II)-Complexes, formaldehyde resin


Article Review Status: Published

Pages: 19-29 (Download PDF)

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