Medication non-adherence results in increased morbidity, mortality and financial loss. Reasons for medication non-adherence are multifactorial. This cross-sectional study was conducted to determine the prevalence of, and factors contributing to medication non-adherence among patients with diabetes mellitus and hypertension attending some secondary and tertiary health care facilities in Lagos, Nigeria. Of the 100 patients, 32% were compliant with their medications. Most (39%) respondents were noncompliant because of lack of funds and cost of medication, 19% due to forgetfulness, 16% because they felt well, and 15% due to non-availability of drugs at the pharmacy. Other reasons for non-compliance include illnesses (9%), side effects of medications (1%) and misinterpretation of prescription (1%). Among the socio-demographic variables studied, only male gender was positively associated with medication compliance. Adherence to anti-diabetics and anti-hypertensives was low. Both health system and patients’ related issues contributed to poor compliance and these should be addressed to improve medication adherence.
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