The role of panax ginseng plant and vitamin D in improving the effectiveness of liver enzymes ALT, AST and ALP in rabbits exposed to X-rays. (Published)
This study was conducted at Animal House, Faculty of Veterinary Medicine\ University of Tikrit , The dosage period was from the beginning of January for (10) days. This study was designed to investigate the protective role of ginseng root and vitamin D3 in animals irradiated by X-ray in rabbits. 50 domestic animals were used from local rabbits Lepus cuniculua domestica Which was obtained from the veterinary hospital at the Ministry of Agriculture – Samarra Agriculture Department, Ranging between 7-9 months and their weights (1250 – 1500 g), The animals were randomly assigned to (10) groups, and each group (5) animals. The (Control) group was the control group where the diet was given with regular drinking water, the Second Group (A): treated with X-ray for one day only, The Third group (B): was treated X-ray and ginseng (150 mg/kg) for one day only, The Fourth group (C) was treated X-ray and ginseng (300 mg/kg) for one day only, The Fifth group (D): was treated X-ray and vitamin D3 (30 IU/kg) for two days only, the Sixth Group (E): X-ray and ginseng (150 mg/kg) and vitamin D3 (30 IU/kg) for only two days, The Seventh group (F): treated X-ray for only two days and left for only 10 days, the Eighth Group (G): was treated X-ray and ginseng (150 mg/kg) for two days and left for only 10 days, The Ninth group (H): was treated X-ray and vitamin D3 (30 IU/kg) for two days and left for 10 days, and the Tenth group (I): was treated X-ray, ginseng (150 mg/kg) and vitamin D3 (30 IU/kg) for two days and left for 10 days.The results of the study showed an increase in the effectiveness of liver enzymes ALP, AST, ALT in X-ray exposed group compared to control group sound. As well as a significant decrease in most studied groups and variance in other groups compared to the group exposed to X-ray.We deduce the obvious effects on the enzymes and hormones of the body as a result of x-ray exposure and increase the oxidative stress on the surface of the cells and the effective protective role of ginseng root and vitamin D3 as effective antioxidants and reduce the damage caused by radiation.
Objective: Vitamin D deficiency and obesity are widely spread and were associated with chronic diseases. The goal of our study is to evaluate the prevalence of vitamin D deficiency in obese individuals and its association with the metabolic parameter. Method:A cross sectional study of individuals attending diet center located in Taif, Saudi Arabia, conducted between October 2015 and June 2016. We included those with BMI >25 and have vitamin D level. Vitamin D ≤ 20 ng/ml was considered to be deficient. Result:A total of 148 participants were enrolled with a mean age of 36 years, mainly female and married .The mean weight was 95.9 kg, mean BMI of 37.3 Kg/m2, 94.6% were obese, and the mean vitamin D level was 15.7. Compared to those who are vitamin D sufficient ,those who are deficient were more likely to have class III obesity (p 0.891), exercise <150 min per week (p 0.453), have asthma (P 0.149), have higher mean total cholesterol level (p 0.310) and higher mean fasting blood glucose (p 0.632). Partial correlation adjusting for age, gender, exercise, diabetes, and hypertension showed non-significant negative correlation between vitamin D and BMI (r -.121, p0.202), vitamin D and cholesterol (r -.039, p 0.678) and vitamin D and blood glucose (r -.122, p 0.198).Conclusion: Non-significant negative correlation was found between BMI and vitamin D level, the average vitamin D level in overweight group was 21 ng/ml while the average in obese class 3 was 15 ng/ml.