Based on the concept of music communication and relevant literature, the paper unravels the communication process in Totoeme musical genre of the Avatime people of Ghana. It attempts to elucidate some of the intrinsic and extrinsic facts in terms of repertoire and general performance of totoeme music. It is an insight into a traditional music phenomenon and some pragmatic but vociferous symbolical elements that enhance meaning in an indigenous musical performance and its associated rituals. Through observation and interview, it was found out that the channels of communication in Avatime music are experienced during procession, choral section, and the dance section in the various contexts. The paper concludes that messages transmitted in the performances during the social occasions portray the artistic cultural values giving opportunities to the people to air their sentiments, emotions and express how their challenges are dealt with.