Tag Archives: Transitions metal complexes

SYNTHESES, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF 4-{[(Z)-(2-METHOXYPHENYL) METHYLIDENE] AMINO}-5-PHENYL- 4H-1, 2, 4-TRIAZOLE-3-THIOLWITH SOME TRANSITION METAL COMPLEXES (Published)

A-new series of transition metal (Cr(III),Fe(III), Co(III), Ni(II)and Cu(II) ) complexes of ligand4-{[(Z)-(2-methoxyphenyl)methylidene]amino}-5-phenyl4H-1,2,4-triazole-3-thiolwere synthesized. All the synthesized complexes were characterized by analytical techniques, magnetic susceptibility measurements, elemental analyses, and conductance, IR, 1HNMR and mass spectra. The electrolytic behavior was confirmed from their conductance data. It may be concluded that the ligand coordinate through nitrogen and sulfur atoms. For all complexes. The ligand acts as a didentate ligand coordinating through the sulfur [S6] and the nitrogen atom of Schiff base [N5]. This view is further supported by the appearance of a band corresponding to the metal–nitrogen stretching vibration at (560–570) cm–1 in the complexes. From results it was suggested tetrahedral geometry for Ni (II) and Cu (II) complexes, while Cr(III),Fe(III) and Co (III)complexes were assigned octahedral geometrics. All complexes and their parent organic moiety have been screened for antibacterial activity by using spread method and inhibition zone measurement by using (DMSO). This study showed positivite inhibition zone results, for both ligand and complexes with E-coli and staph aurens.

Keywords: Antibacterial, Transitions metal complexes, Triazole