Nowadays, Vietnam’s tourism has attracted international visitors very strongly. Because Vietnam is a politically and economically stable country, people are friendly and rich in cultural identity. However, it is facing many problems such as incomplete infrastructure, human resources, service quality, technology capacity… This reality requires each tourism enterprise to constantly improve its competitive capability to compete not only domestic but also foreign tourism enterprises. Therefore, the study objective is to find out the determinants affecting the competitive capability of tourism enterprises in Ho Chi Minh City (HCNC). The researcher surveyed 500 tourists using the services of tourism enterprises and answered 23 questions but sample size of 457 tourists processed. The data collected from July 2018 to March 2019 in HCMC. Simple random sampling technique. Cronbach’s Alpha and the exploratory factor analysis (EFA) analyzed and used for Structural Equation Modelling (SEM) technique. Finally, the findings of the study have five factors affecting the competitive capability of tourism enterprises with significance level 0.01.