Saving deposits have a very important meaning to the bank because it is the basis for the bank to bring profits through investments, loans, reserves… Therefore, it is important for commercial banks to ensure maximum customer satisfaction with the services that the bank provides. The study objective is to find out the determinants affecting the deposit service quality of Joint Stock Commercial Bank for Investment and Development of Vietnam (BIDV) in Can Tho City. The researchers surveyed 350 customers using deposit services of BIDV answered 28 questions but 331 customers processed. The primary sources of data collected from July 2018 to April 2019 in Can Tho City. Simple random sampling technique. The Data analyzed Cronbach’s Alpha and the exploratory factor analysis (EFA), which used for multiple linear regression and using partial least squares method. Customers’ responses measured through an adapted questionnaire on a 5-point Likert scale. In addition, the findings of the study have six factors affecting the deposit service quality of BIDV in Can Tho city with significance level 0.05.