Tag Archives: non-adherence

Determinants of Non-Adherence to Drug Regimen among TB Patients Attending a Specialist Hospital, Edo State Nigeria (Published)

Tuberculosis is one of the leading causes of death globally and in Nigeria that poses a threat. This study examine the determinants of non- adherence to drug regimen among TB patients in a Specialist Hospital, Edo state. The study adopted a descriptive research design. A simple random sampling technique was used in selecting the respondents of the study.  The data were collected through the use of questionnaire with reliability index of 0.78. The data collected were analyzed using descriptive statistics of frequency, simple percentage and inferential statistics (chi-square). The findings of the study revealed that 222 (56.6%) respondents do not adhere to drug regimen while 171 (43.5%) does. There was a significant relationship between distance of health facility (p=0.001), waiting time (p=0.000), absence of family support( p=0.000), forgetfulness (p=0.000) , individual’s occupation (p=0.000), improvement in TB symptoms( p=0.000) and non-adherence to TB drugs but client provider interaction and TB drug side effect do not have a significant relationship on non-adherence to TB drugs. The study recommends that government should make TB clinic should accessible by building and employing enough health workers. Also, families should be encouraged to support TB patients and TB patients on TB drugs should be educated on the needs to comply with drugs and not to discontinue it even when symptoms improve.

Keywords: Determinant, Drugs, Tuberculosis, non-adherence

Influence of Demographic and Socio-Cultural Variables on Non-Adherence to Anti-Retroviral Therapy (ART) Among HIV/AIDS Patients Attending a Government Owned Hospital, Ondo State, Nigeria (Published)

An anti-retroviral therapy adherence of at least 95% has been proven necessary in order for treatment to be effective. Failure to meet this level leads to poor immunological and virological outcome. This study assessed the influence of demographic and socio-cultural variables on non-adherence to anti-retroviral therapy (art) among HIV/AIDs patients attending a government owned hospital in Ondo State, Nigeria using a descriptive research design. A total number 110 respondents were recruited using a convenience sampling techniques. Questionnaire with reliability index of 0.70 was used as an instrument for data collection. Data were analyzed using statistical package for social science (SPSS). Descriptive and inferential statistics were used to test the hypotheses. Results were presented in tables and figures.  Findings showed that 66(60%) adherence to anti-retroviral therapy which is below 95% adherence rate and 44(40%) do not adhere to ART.  The outcome of this study further established that there was a significant relationship between gender (p=0.00), level of education (p=0.00), family support ( p=0.00), cultural factor( p=0.00),  religion (p=0.00), employment status ( p=0.00), poverty ( p=0.00) and noncompliance with ART, however, there was no relationship between age (p= 0.26 ), access to clinic (0.31) and non-adherence to ART. This study concluded that, HIV/AIDS patients should therefore be supported in all aspects to promote compliance with the use of Anti-Retroviral Drugs.

Keywords: HIV/AIDS, Patients, anti-retroviral, non-adherence