This paper submits that the problem of suffering is a perennial one. It cuts across every nation, race and people of the world. Different arguments from the different worldviews such as Buhdist, existentialist and the African thought system were examined to analyze the problem that bothers on the existence of man in the world. Beyond that, emphasis was laid on the notion of ignorance as the basis for human suffering. This paper also suggests ways through which people can alleviate or stop their suffering especially in the face of man inflicted suffering on others.