Correlation of Serum Lipid Profile with Serum Iron, Tibc & Ferritin Levels in Beta Thalassemia Major Patients (Published)
Correlation of serum lipid profile with serum iron, TIBC & ferritin levels in beta thalassemia major patients. Background- Beta thalassemia major, a common disorder, causes severe anemia. This is treated by regular blood transfusion, leading to iron overload and increased serum ferritin. There is considerable variation between studies as to the serum lipid levels in these patients. Aims- The study was carried out to observe the alteration of serum lipid levels and also whether the alteration could be correlated with ferritin and other hematological indices. Methods and materials-The study was carried out on 50 beta thalassemia major patients and 47 controls. Estimation of serum lipid profile, iron, ferritin, TIBC (Total iron binding capacity), hemoglobin and hematocrit was done. Statistical analysis-Data analysis was performed using standard methods. Results-Compared to controls, the cases had significantly higher ferritin and significantly lower HDL-C (high density lipoprotein- cholesterol) levels. There was inverse correlation between high ferritin and low HDL-C levels. Conclusion-Taken together, high ferritin and low HDL-C levels might be important predictors for mortality in thalassemia.
Determination of Mineral Contents of Edible Parts of Shellfishes from Okpoka Creeks in Rivers State, Nigeri (Published)
The study was conducted to determine the mineral contents of some selected shellfishes from Okpoka Creek in River State. Copper, iron, manganese, calcium and sodium were quantified using Atomic Absorption Spectrophotometric method and the concentration of the minerals varied between the different species of shellfishes. High amount of calcium was recorded in C. guanhumi (212.33±1.45mg/100g) while the lowest was observed in T. fuscatus (48.39±1.4mg/100g). The manganese content was higher in T. coronata (1.82±0.10 mg/100g) and lower in T. fuscatus (0.25±0.11mg/100g). Meanwhile the iron content was more in C. gasar (29.5±0.5mg/100g) and lower in C. amnicola (8.07±1.485mg/100g). However, T. coronate showed higher content of copper (10.15±0.17mg/100g) while the lowest copper content was observed in T. fuscatus (2.15±0.43m g/100g). C. amnicola (115.9±0.26mg/100g) recorded the highest amount of sodium while T. coronate (17.43±0.11mg/100g) recorded the least sodium content. The results suggest that these shellfishes are nutritious and are valuable additions to our diet.
The Structural Characterizations of Polymethel(Methaacrylate) Doped Nanoparticle Metal (Cu,Co,Fe) Thin Film by Using Nd-Yag Laser Ablation (Published)
The structural properties of PMMA doped with ( Cu , Co , Fe ) nanoparticls prepared by laser ablation were studied . In this research the polymethyl mehtacrylate (PMMA) was dissolved in chloroform with (5%) concentration to form homogeneous solution. PMMA doped with (Cu ,Fe ,and Co ( nanoparticale (NPs) prepared by Nd-Yag(532nm) laser ablation. The X-ray diffraction shows that the structure of pure polymer film have an amorphous nature, but PMMA doped with (Cu , Co , Fe) nanoparticles are polycrystalline structure. The results indicate that there are a shifting and reduction in positions of peak intensity as compared with the pure (Cu , Co ,Fe) nanoparticles and there are generated some new peaks appear. The AFM examination reveal to reduction in average nanoparticle diameter after doping with NPs metal (Cu , Co , Fe ) . The FT-IR examination appear some transmittance band after doping with NPs metal (Cu , Co , Fe )