A linguistic analysis of selected antibiotic information leaflets examined the language structures in composing the information of both manufacturing and marketing drug companies in Nigeria. These companies on which their leaflets are studied are Emzor, Jawa, Cika, Transglobe and Taylek. A descriptive design was adopted for the study and the models of Crystal and Davy (1985) and Leech and Short (1981) were used toanalyse the pattern of interlocking grammatical systems, from the smallest units of words and phrases to larger unit of sentences. The study examined and analysed syntactic structures in the formation of linguistic sentences used on the information leaflets, which varied in different sentence types that provide meaningful explanation about the chemical compositions of the produced drugs. Relatively, it determined the sense relations of the connected sentences and the graphological features contained on the leaflets. Conclusively, it was stated that the language used in the construction of sentence is complex in nature due to over use of chemical terms. It was recommended that leaflets should be written in simple sentence devoid of complexity for drug user’s comprehension.