This article will explain what the challenges are in the global postal network (GPN). GPN play a significant role in the global supply chain and try to fulfill the needs of SMEs while entering foreign markets. Postal operators with their networks help to facilitate international trade to deliver parcels, packages, partnering with express, courier services embracing mobile and online technologies, provide financial services etc. The few examples will be mentioned how the post can help to facilitate business for SMEs, because GPN is an integral part of the overall e-commerce today. Some innovative ideas will be presented how the national posts are trying to support especially e-business not only on the local market but also abroad.