Building collapses in Nigeria have been on the increase in recent times. There are frequent media reports of collapsed of buildings in major Nigerian cities like Lagos, Abuja, and Port Harcourt, etc and other parts of the world. In an attempt to find lasting solutions to tackle the challenges, this paper examines causes of building collapse in Nigeria and also enumerated specific areas the stakeholders in the building industry and the general public are affected. The problems range from faulty design, negligence, incompetence, faulty construction, foundation failures, extraordinary loads and corruption. Forces of nature were also identified as part of causes of building collapse. Some recommendations were made as part of lasting solutions to tackle the challenges.