Tag Archives: Cobalt (II)-complexes.

Synthesis, Characterization, Biological Activity And Thermal Degradation Of (Benzyl -; P-Chlorobenzyl-)Dithiocarbamate And 1,10-Phenanthroline Mixed Ligands Complexes (Published)

A new Cobalt (II) and Cupper (II) complexes with mixed ligands including [benzyl – (dtc1) ; p-Chlorobenzyl- (dtc2)] dithiocarbamate and 1,10- phenanthroline (phen) have been prepared by reacting CoCl2.6H2O and CuSO4.5H2O with appropriate mole ratio of these ligands .These complexes have been characterized by elemental analysis ,1H NMR , infrared , electronic spectra ,X-ray diffraction(XRD) , thermal analysis and tested for anti- bacterial activity against several bacterial strains , namely staphylococcys aureus and Escherichia coli . The results suggest an octahedral structure for all the mixed ligands complexes with two nitrogen donor atoms of heterocyclic compound ( 1,10- phenanthroline) as well as sulpher of dithiocarbamate.

Keywords: Cobalt (II)-complexes., Copper (II) Complexes., Dithiocarbamate, Mixed Ligand Complexes, Phenanthroline

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF TWO PHENOL- SCHIFF BASES AND FORMALDEHYDE RESIN COBALT (II) – COMPLEXES (Published)

Transition metal, cobalt (II) acetate, complexes of salicylaldehyde derived Schiff bases: 2-{[(2- hydroxophenyl) imino] methyl} phenol (OHMP), 2-{[ (2- carboxy- phenyl) imino] methyl} phenol (COOHMP), and anthranilic acid- formaldehyde resin (R-COOHMP) were synthesized and characterized by various analytical and spectroscopic studies ( FT-IR, UV-Visible and 1H NMR ). The Schiff base ligands, formaldehyde chelating resin and their Co(II) complexes were also screened for their urease, α – chymotrypsin, acetylcholinesterse and butylrylcholinesterase inhibition activities.The ligands were found active against two bacterial species: Staphylococcus aureus and Escherichia coli, all theligands and complexes were evaluated for their thermal degradation studies using TG- DTA analytical methods in static air.

Keywords: Biological Activity, Cobalt (II)-complexes., formaldehyde resin