Effects of Epigenetic Groups & Chromosomal Proteins on Human Genome Expression by way of its genes and Universal Reactions of Matter (Published)
When chemical compounds are added onto single genes, they attach or bind to a gene/s or chromosomal proteins. The attachment or binding of these chemicals cause modifications or changes in the activities of the genes (with no change in DNA sequence). These functional changes of the genes are referred to as Epigenetic Modifications whereas the study of the epigenetic modification and its causative agents is known as Epigenetics. The epigenetic group (chemical) attached to a gene regulates the function of the gene without any change in the DNA sequence. The key objective of this study is to impart the fact that human Genome is a supersensitive molecular machine based on its responses to epigenetic groups & chromosomal proteins. Cancer is a group of diseases arising in part from:
►1. Chromosomal abnormalities and mutations in tumor-suppressor genes & oncogenes, and
►2. Epigenetic modifications.
The main aim of universal reactions of matter is to improve or to make better the living standards and to create the safest conditions possible for humans in each country of the planet (Earth). Based on the main aim of universal reactions of matter, China has become the model country on Earth with surprising & drastic growth in economy, science and technology; and also, being one of the safest countries in the world for its residents & tourists.
Citation: Feleke Eriso (2022) Effects of Epigenetic Groups & Chromosomal Proteins on Human Genome Expression by way of its genes and Universal Reactions of Matter, European Journal of Biology and Medical Science Research, Vol.10, No.3, pp.26-58,
The Place of Environmental Literacy Education in Cancer Prevention among Rural Nigerian Communities (Published)
This paper is intended to portray the capacity of Environmental Literacy Education towards cancer prevention in Nigeria, particularly among the country’s rural communities. Reliable data from the World Health Organization show that about 1 in 6 deaths is due to cancer globally. For Nigeria, information from the Global Cancer Observatory affirms that cancer is responsible for about 72,000 deaths annually in the country. The rural communities in Nigeria have been shown in this paper to be very much vulnerable to cancer from various sources due to a host of social and economic deprivations, unfavourable environmental factors as well as mass illiteracy and cancer unawareness. Nigeria’s cancer prevention and care framework is an advocacy/awareness creation strategy which, unfortunately, lacks some vital content and delivery format. Following detailed analysis of the content, process and outcomes of Environmental Literacy Education (ELE) and its great potential to adequately inform/educate the rural community members about the nature and incidence of cancer and their individual/collective roles towards cancer prevention within their environment, the paper concludes and also recommends that ELE should occupy the pride of place in cancer prevention within Nigeria’s rural communities. The paper also suggests and expatiates on the various modes (Formal, Non-Formal and Informal) through which the required ELE could be effectively implemented.
Caroline Lewechi Eheazu and Ifeoma Felicia Uzoagu (2021) The Place of Environmental Literacy Education in Cancer Prevention among Rural Nigerian Communities, International Journal of Cancer, Clinical Inventions and Experimental Oncology, Vol.3, No.1, pp.1-23
As people with cancer disease, beyond the side effects of treatments, uncertainties regarding the future, suffering, physical pain, anxiety, depression, loss of control and autonomy. The nurse must interact with how people, inserted in their sociocultural context, who are in a situation of health / illness transition. The intervention instituted in the present work was a therapeutic massage, due to the help to restore the physical and psychic balance. The application of massage and the maintenance of hygiene care and comfort and development, as well as the application of the complementary practice to the strategy of self-care and harmonization. We designed a quasi-experimental study whose objective is to evaluate the effect of therapeutic massage on mental health in a sample of 31 cancer patients, 16 in the experimental group and 15 in the control group. The selection criteria of this study considered research on this theme, so that we can have models of comparison of results. Therefore, the inclusion criteria were patients aged between 18 and 65 years old, included in an outpatient clinic, with a medical diagnosis of cancer and with a cognitive ability to self-fill the questionnaires. For this the Mini Mental State Examination Scale was applied. There are some pathologies, signs and symptoms in which this intervention is contraindicated, namely: Patients with circulatory problems, varicose veins; inflammatory or fungal processes; fever or hyperthermia; on treatment with chemotherapy; post-surgery, post-radiotherapy, post-stroke or post-myocardial infarction; bone pathology (fractures, recent torsion); hypertension; hemophiliacs; localized contagious or dermatological diseases. For the operation of the independent variable, a therapeutic massage protocol recommended by Tiffany Field and Hernandez-Reif was used, and to evaluate the dependent variable, we used the Brief Pain Inventory, which revealed good internal consistency. This study revealed a beneficial effect of therapeutic massage with regard to pain, we showed a significant improvement in pain intensity (p <0.001) and pain interference (p <0.001). We intend with this study not only that health professionals use this intervention, as well as that these results encourage the scientific community, in the conduct of future research in this pathology and in other chronic pathologies.
An Assessment of Undergraduates’ Nutrition Awareness Level on the Scourge of Cancer as a Current Devastating Phenomenon in Nigeria (Published)
The prevalence of cancer continues to increase in Nigeria. The factors that appear to be most responsible are poor nutrition and sedentary lifestyle. Therefore, this study examined the undergraduates’ nutrition awareness level on the scourge of cancer as a current devastating phenomenon in Nigeria. A descriptive research design was adopted for the study. A total of 600 undergraduates were selected through stratified and random sampling techniques from 3 universities in Ogun State, Nigeria. A self-developed questionnaire and pilot-tested was used to collect relevant data from the respondents. The data gathered from the study were analysed using descriptive and inferential statistics. The results revealed that Nigerian undergraduates are not well informed on the importance of nutrition in the prevention of cancer. Also, socio-personal characteristics such as gender, discipline, and school type significantly did not influence on how informed the undergraduate students are on disease prevention and making adequate food choices. In view of the outcome of the findings in this study, it is recommended that public health education be intensified to promote people’s awareness of the consequences of poor nutrition and sedentary lifestyle; and making healthy food choices.
The Social Issues among Adult Cancer Patients Attending Oncology Clinic at Moi Teaching and Referral Hospital, Eldoret, Kenya (Published)
Cancer diagnosis is associated with increased chance of developing social issues that impact on patient’s health state and medical treatment. The number of people diagnosed with cancer is on the increase every year in the developing countries with no exception of Kenya. The burden of cancer continues to grow. However, as much as social issues among adult cancer patients are well documented in the rest of the world, Kenya has little amount of data in place. A critical part of cancer care is the recognition of the levels of social problems that present among patients with cancer and determination of the appropriate form of intervention, ranging from brief counselling or social interventions and social support to medication and specific coping styles. This paper sought to determine the social issues among adult cancer patients seen at the oncology clinic of Moi Teaching and Referral Hospital (MTRH), Eldoret. Focus was on the social issues that are associated with cancer diagnosis and socio-demographic characteristics and clinical state of the patients diagnosed with cancer. This was a cross-sectional and descriptive study. The respondents included patients diagnosed with cancer who were enrolled and interviewed using researcher designed socio-demographic and clinical questionnaire and the Mini International Neuropsychiatric Interview for adults (M.I.N.I Plus) instruments. A total of 138 respondents participated in the study. The participants were assessed upon an informed consent and ethical approval from Institutional Research and Ethics Committee (IREC) Moi Teaching and Referral Hospital (MTRH) Moi University and Ethics and Research Committee Kenyatta National Hospital/ University of Nairobi.Microsoft excel worksheet and Statistical packages for social sciences (SPSS) version 16.0 were used for analysis. Females represented a higher number of cancer patients than male. Breast cancer and cervical cancer were the most common forms of cancer with most participants being in the advanced stages; between stage III and IV. Social phobia, obsessive compulsive disorder, generalised anxiety disorder, hypomanic episodes and manic episodes were the most observed social disorders.