Tag Archives: BMI

Comparison of anthropometric measurement and total cholesterol in calcific aortic stenosis (Published)

Background and objective: Changes in the lipid concentration can be reflected by anthropometric measurements. The present study is aimed to determine the relationship of anthropometric measurement and total cholesterol in calcific aortic stenosis. Methods: A case-control study in which 208 calcific AS patients were recruited from echocardiography department and OPD from NICVD  and 208 age and gender matched controls were selected. Complete physical and medical examination was carried out including the demographic profile and anthropometric measurements. Total cholesterol was done in Biochemistry section of DDRRL, Ojha Campus. Statistical analysis was conducted on SPSS 21. Mean and standard deviation were calculated for all the continuous variables including age, WHR, BMI and total cholesterol.t-test was applied to compare the WHR, BMI and total cholesterol between cases and controls. Pearson correlation was used to see the leaner correlation of BMI and WHR to total cholesterol. Results: Mean age for the cases was 67.12 years ±5.08 and for controls was 66.74 years ± 3.71. There were 67.8% male and 32.2% female in the case group and 64.9% male and 35.1% female in control group.There was significant difference in BMI and WHR of cases and controls with significant p- value while total cholesterol showed insignificant difference. BMI shows significant but positive weak correlation with total cholesterol in cases as well as in controls.  While WHR shows insignificant correlation in cases and control group indicates significant but positive weak correlation. Conclusion: Increase in total cholesterol may be an indicator of increase in BMI and WHR.

Keywords: BMI, WHR., anthropometric measurements, calcific aortic stenosis, total cholesterol

THYROID METABOLIC HORMONES AND ITS CORRELATION WITH BMI AND LIPID PROFILE IN HEALTHY PEOPLE (Published)

Background: Thyroid hormone play an important role in basal lipid metabolism.It is well known that alteration in thyroid function can result in changes in the composition and in the transport of lipoprotein.This study aimed to study the effects of thyroid hormone on serum lipids and evaluted the correlation between thyroid hormone with Body Mass Index (BMI) and lipid profile of healthy people. Methods: Total of 56 healthy people(28 male:28 female) ,aged 30-60 years included in this study.About 5ml of fasting blood (8-12 h.) was collected from each individual.To determine serum Thyroid stimulating hormone (TSH), Triiodothyronine (T3) and Thyroxine (T4) and the quantitative sandwich enzyme immunoassay technique were used.Lipid profile were measured by an enzymatic colorimetric(GPO-POD) method. Results:The result of the present study showed that the levels of triglyceride was significantly higher (p< 0.05) in males than females ,while the levels of triiodothyronine was significantly higher(p< 0.05) in females than males of healthy people.Correlation analysis in healthy males showed positive correlation among BMI with lipid profile,while an inverse correlation between TSH and T4,also an inverse correlation between T3 and HDL .In healthy females there was positive correlation among T3 with BMI and WC,also between T4 and LDL ,while an inverse correlation between TSH and VLDL. Conclusions: Thyroid metabolic hormone especially T3 regulate the resting metabolic rate and the mild thyroid dysfunction was linked to significantly changes in body weight ,lipid profile and likely represents risk factor for healthy and obesity

Keywords: BMI, Healthy people, Lipid profile, Thyroid metabolic hormone

Thyroid Metabolic Hormones and its Correlation with BMI and Lipid Profile in Healthy People (Review Completed - Accepted)

Background:Thyroid hormone play an important role in basal lipid metabolism.It is well known that alteration in thyroid function can result in changes in the composition and in the transport of lipoprotein.This study aimed to study the effects of thyroid hormone on serum lipids and evaluted the correlation between thyroid hormone with Body Mass Index(BMI) and lipid profile of healthy people.

Methods:Total of 56 healthy people(28 male:28 female) ,aged 30-60 years included in this study.About 5ml of fasting blood (8-12 h.) was collected from each individual.To determine serum Thyroid stimulating hormone (TSH), Triiodothyronine (T3) and Thyroxine (T4) and the quantitative sandwich enzyme immunoassay technique were used.Lipid profile were measured by an enzymatic colorimetric(GPO-POD) method.

Results:The result of the present study showed that the levels of triglyceride was significantly higher (p< 0.05) in males than females ,while the levels of triiodothyronine was significantly higher(p< 0.05) in females than males of healthy people.Correlation analysis in healthy males showed positive correlation among BMI with lipid profile,while an inverse correlation between TSH and T4,also an inverse correlation between T3 and HDL .In healthy females there was positive correlation among T3 with BMI and WC,also between T4 and LDL ,while an inverse correlation between TSH and VLDL.

Conclusions:Thyroid metabolic hormone especially T3 regulate the resting metabolic rate and the mild thyroid dysfunction was linked to significantly changes in body weight ,lipid profile and likely represents risk factor for healthy and obesity.

 

Keywords: BMI, Healthy people, Lipid profile, Thyroid metabolic hormone