This study aims to investigate secondary school students’ attitudes in Saudi Arabia towards science. Questionnaire of 24 items was developed considering a variety of attitudes toward science instruments, and then administrated to a sample of 150 secondary school students (78 males & 72 females). The findings indicated that secondary school students in Saudi Arabia have positive attitudes towards science. At the meantime, the results showed that there was no significant difference in attitudes towards science between males and females. These findings are discussed in the context of science teaching and research. In addition, the results suggest that further research is required to explore how Saudi students’ positive attitudes towards science can be used to improve their performance in science.