The earlier studies have shown that zinc deficiency can hinder host-defense systems to increase the susceptibility to various viral and bacterial infections, and thus in view of the global COVID-19 pandemic, potential protective effect of zinc is of particular interest. As it has become clear that zinc deficiency is induced by the non-transferrin-bound iron (NTBI) based on the our works, the use of our non-toxic iron chelators can be recommended as the supportive treatment in therapy of COVID-19 infection, because our iron chelators may prevent the zinc deficiency by inhibiting the formation of iron deposition containing much iron and zinc ions through removing or controlling the iron(III) ions in NTBI.
Keywords: Anti-oxidant Function, COVID-19, NTBI and Iron Deposition, Zinc
