This study is designed to evaluate the effect of ethanolic extract of Cassava (Manihot esculenta, crantz) on biochemical profile of Albino Rats. Four varieties of cassava leaves were used: two for sweet cassava (TMS 98/0505, TME 419) and two for bitter cassava (TMS 98/0002, NR 8082). Eighty Wistar Albino Rats of both sexes weighing 150-200g were used. The animals were orally infected with human intestinal parasites. They were randomly divided into 5 groups and subjected to different treatments. The results showed that sweet cassava varieties caused significant decrease (P<0.05) in the valves of ALT, ALP and CRT, while bitter cassava varieties caused significant increase (P<0.05) in the levels of ALT, ALP and CRT in the treated groups when compared with control. The ethanolic extract of the Sweet Cassava Varieties protected the liver and kidney of Albino Rats from damage caused by intestinal parasitic infections. These Varieties are useful phytomedicines for controlling intestinal parasite infections.
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