Possible Anti-Hemolytic and Antioxidnt Role Of Ethanolic Extract Of Coriander On Irradiated Rats


Foods wealthy in antioxidants play an essential role in the prevention of diseases.Coriander (Coriandrum sativum L.), a conventional annual herb selected for assessing antihemolytic and antioxidant properties. To study the effectiveness of Coriandrum sativum as an antihemolytic and antioxidant agent, the oxidative stress was induced in rats by gamma radiation exposure with 4 Gy shot dose after 14 days oral administration of coriander extract (600 mg/kg b.wt). Exposing rats with 4 Gy gamma rays was significantly decreased RBCs, WBCs and Platelets counts. But the percentage of segmented cells as well as the activity of serum aspartate transaminase (AST) and endothline 1 (ET1) level was significantly increased after radiation exposure. Interestingly, among the tested parameter, the ethyl extract of coriander showed marked improvement in both haematological and biochemical changes. In conclusion, addition of coriander to food will increase the antioxidant content and may have potential as a natural antioxidant and thus inhibit unwanted oxidation processes.

Keywords: Antihemolytic, Antioxidant, Antioxidants, Coriandrum sativum L., Flavonoids, Gamma radiation

Unique Article ID: EJBMSR-120
Article Review Status: Published

Pages: 39-48 (Download PDF)

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